ruin

/ˈɹuː.ɪn/

(sometimes in the plural) The remains of a destroyed or dilapidated construction, such as a house or castle.

The state of being a ruin, destroyed or decayed.

The monastery has fallen into ruin.

Something that leads to serious trouble or destruction.

Gambling has been the ruin of many.

A fall or tumble.

A change that destroys or defeats something; destruction; overthrow.

the ruin of a ship or an army;  the ruin of a constitution or a government;  the ruin of health or hopes

Complete financial loss; bankruptcy.