misery

/ˈmɪz(ə)ɹɪ/

Great unhappiness; extreme pain of body or mind; wretchedness; distress; woe.

Ever since his wife left him you can see the misery on his face.

A bodily ache or pain.

Cause of misery; calamity; misfortune.

(Extreme) poverty.

Greed; avarice.